Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 6/20 | 0.56 |
| ▸ | GABRD | O14764 | 6/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.56 |
| ▸ | GABRE | P78334 | 6/20 | 0.56 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.56 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.56 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.56 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996174 | 0.80 | MAOB (0.51) | CA12CA9MEN1MAPTKMT2A | |
| SCHEMBL28154853 | 0.77 | CYP2A6 (0.50) | MEN1MAPTKMT2AVCAM1 | |
| SCHEMBL6957384 | 0.75 | ADCY1 (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7538912 | 0.75 | GABRP (0.84) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9189119 | 0.74 | KDM1A (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4252552 | 0.73 | ALDH1A1 (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8123062 | 0.73 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6956680 | 0.73 | TNKS (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6656060 | 0.72 | GABRP (0.82) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6957571 | 0.72 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634409-B1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | claimed |
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | claimed |
| EP-0634409-A1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | claimed |
| EP-0711762-B1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-6277998-B1 | REACTING 2-CYANO-4-OXO-4H-BENZOPYRAN COMPOUND WITH HYDROGEN SULFIDE AND THEN REACTING PROUDCT WITH ALKYL HALIDE; REACTING THE PRODUCT WITH HYDRAZINE OR ITS SALT AND THEN WITH NITROUS ACID COMPOUND TO OBTAIN TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6191289-B1 | REACTING A 4-OXO-4H-BENZOPYRAN GROUP SUBSTITUTED WITH AMIDE OR A PHENYL GROUP IN ITS 2 POSITION IS REACTED WITH ANHYDROUS HYDRAZINE OR SALT IN PRESENCE OF CATALYST FOLLOWED BY REACTING WITH NITROUS ACID OR SALT TO FORM TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0634409-B1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5874593-A | SULFUR CONTAINING AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0711762-A1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUND AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0634409-A1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |