Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.78 |
| ▸ | BACE1 | P56817 | 1/20 | 0.76 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.64 |
| ▸ | HRH1 | P35367 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476820 | 0.87 | LTA4H (1.00) | LTA4HMCHR1HTTHRH3KCNH2 | |
| SCHEMBL7447086 | 0.86 | HRH3 (0.71) | LTA4HBACE1MCHR1HRH3KCNH2 | |
| SCHEMBL20748052 | 0.86 | LTA4H (0.97) | LTA4HMCHR1HTTHRH3KCNH2 | |
| SCHEMBL4688871 | 0.86 | LTA4H (0.97) | LTA4HMCHR1HTTHRH3KCNH2 | |
| SCHEMBL1899201 | 0.84 | LTA4H (1.00) | LTA4HBACE1HRH3KCNH2HRH1 | |
| SCHEMBL14970484 | 0.83 | LTA4H (0.97) | LTA4HBACE1HRH3KCNH2HRH1 | |
| SCHEMBL16346074 | 0.83 | GSTP1 (0.66) | — | |
| SCHEMBL6955456 | 0.82 | LTA4H (0.72) | LTA4HBACE1HRH3KCNH2HRH1 | |
| SCHEMBL21462645 | 0.82 | HRH3 (0.86) | LTA4HBACE1HRH3KCNH2HRH1 | |
| SCHEMBL7436764 | 0.81 | LTA4H (0.71) | LTA4HBACE1HRH3KCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0980366-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| EP-0980366-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| WO-1998049160-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |