Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387029 | 0.74 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL7007764 | 0.69 | SLC6A2 (0.37) | SLC6A4SLC6A3KMT2A | |
| SCHEMBL11516122 | 0.69 | KMT2A (0.41) | ALDH1A1HPGDCYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL6541853 | 0.69 | DAO (0.36) | DAOALDH1A1HPGDCREBBPALOX5 | |
| SCHEMBL6541207 | 0.69 | DAO (0.36) | DAOALDH1A1HPGDCREBBPALOX5 | |
| Hydrochloric Acid SCHEMBL6336901 | 0.68 | SLC6A2 (0.36) | ALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL12296177 | 0.68 | PNMT (0.37) | DAOALDH1A1ALOX5SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6541046 | 0.68 | SLC6A2 (0.36) | ALDH1A1SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6540298 | 0.68 | SLC6A2 (0.36) | ALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL4443246 | 0.67 | CYP2D6 (0.37) | SLC6A4SLC6A3CYP2D6GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787543-B2 | PREPARATION OF TACHYKININ ANTAGONISTS; SUBSTITUTED NITROGEN-CONTAINING HETEROCYCLES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| US-20030176430-A1 | Benzhydryl derivatives | ASTELLAS PHARMA INC. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1294700-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000631-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176430-A1 | Benzhydryl derivatives | BDKRB1, BDKRB2, TACR1 | DAO 1046/4885ALDH1A1 2029/4885HPGD 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.