Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 4/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 2/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | BMX | P51813 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955562 | 0.95 | SRD5A1 (0.37) | SRD5A1SRD5A2ABL1LCKKDR | |
| SCHEMBL6957761 | 0.93 | TP53 (0.40) | SRD5A1SRD5A2SMN1; SMN2 | |
| SCHEMBL6970019 | 0.91 | SMN1; SMN2 (0.37) | ABL1LCKKDRFYNSRC | |
| SCHEMBL6958474 | 0.89 | RORC (0.36) | SMN1; SMN2 | |
| SCHEMBL6964622 | 0.88 | SMN1; SMN2 (0.37) | SRD5A1SRD5A2APPSMN1; SMN2 | |
| SCHEMBL6954411 | 0.88 | SMN1; SMN2 (0.39) | SRD5A1SRD5A2KDRFYNSRC | |
| SCHEMBL6959003 | 0.88 | TP53 (0.41) | SRD5A1SRD5A2SMN1; SMN2 | |
| SCHEMBL6961412 | 0.87 | SMN1; SMN2 (0.37) | ABL1LCKFYNSRCBCR | |
| SCHEMBL6961519 | 0.86 | KMT2A (0.33) | KDRFYNSMN1; SMN2RXFP1 | |
| SCHEMBL6966508 | 0.86 | KMT2A (0.37) | LCKKDRMAPK14FYNSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |