Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 12/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR1E | P28566 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597985 | 0.88 | GRM2 (0.38) | GRM2MAOBTMEM97SIGMAR1HTR1A | |
| SCHEMBL6208617 | 0.81 | NPC1 (0.42) | GRM2TMEM97SIGMAR1HTR1AADRA2A | |
| SCHEMBL5326969 | 0.80 | MAOB (0.51) | MAOB | |
| SCHEMBL6961081 | 0.79 | MAOB (0.41) | GRM2MAOB | |
| SCHEMBL6964490 | 0.79 | MAOA (0.46) | GRM2MAOBTMEM97SIGMAR1HTR1A | |
| SCHEMBL27458038 | 0.79 | MAOA (0.46) | GRM2MAOBTMEM97SIGMAR1HTR1A | |
| SCHEMBL6962353 | 0.79 | MAOA (0.40) | GRM2MAOBTMEM97SIGMAR1HTR1A | |
| SCHEMBL6971209 | 0.78 | GRM2 (0.35) | GRM2MAOBTMEM97SIGMAR1HTR1A | |
| SCHEMBL6956015 | 0.77 | MAOB (0.44) | GRM2MAOBTMEM97SIGMAR1HTR1A | |
| SCHEMBL6972550 | 0.76 | GRM2 (0.38) | GRM2MAOBTMEM97SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181288-B1 | BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT | UPJOHN CO (US) | 2003-07-30 | — | — | EP | disclosed |