⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL603100 | 0.80 | — | — | |
| SCHEMBL4630955 | 0.75 | CHRNB2 (0.35) | — | |
| SCHEMBL3891537 | 0.75 | CHRNB2 (0.35) | — | |
| SCHEMBL18425610 | 0.75 | SIGMAR1 (0.59) | — | |
| SCHEMBL1225130 | 0.71 | USP2 (0.39) | — | |
| SCHEMBL6880271 | 0.69 | — | — | |
| SCHEMBL7786235 | 0.69 | KMT2A (0.38) | — | |
| SCHEMBL1476813 | 0.68 | — | — | |
| SCHEMBL7344795 | 0.66 | GLA (0.35) | — | |
| SCHEMBL15967513 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| WO-1996033723-A2 | USE OF BENZAMIDE DERIVATIVES FOR TREATING AND/OR PREVENTING MENIERE'S SYNDROME AND MOTION SICKNESS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |