Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.40 |
| ▸ | NPR3 | P17342 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961818 | 1.00 | PABPC1 (0.42) | PABPC1SCN9ANPR3P2RX7CTSS | |
| SCHEMBL6955840 | 0.93 | KLK7 (0.41) | PABPC1SCN9ACTSS | |
| SCHEMBL6955835 | 0.93 | KLK7 (0.41) | PABPC1SCN9ACTSS | |
| SCHEMBL6968920 | 0.92 | KLK7 (0.42) | PABPC1SCN9AP2RX7KDM4EMAPT | |
| SCHEMBL6968925 | 0.91 | SCN9A (0.34) | PABPC1SCN9A | |
| SCHEMBL6955844 | 0.91 | SCN9A (0.35) | PABPC1SCN9ANPR3 | |
| SCHEMBL6962443 | 0.91 | KLK7 (0.35) | PABPC1SCN9AACE | |
| SCHEMBL7688087 | 0.90 | POLB (0.39) | PABPC1SCN9AKDM4EMAPTKMT2A | |
| SCHEMBL7688088 | 0.90 | POLB (0.39) | PABPC1SCN9AKDM4EMAPTKMT2A | |
| SCHEMBL6967519 | 0.89 | SCN9A (0.35) | PABPC1SCN9ANPR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |
| EP-1015444-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998043968-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1998-10-08 | — | — | WO | disclosed |