Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.35 |
| ▸ | FLT4 | P35916 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 2/20 | 0.31 |
| ▸ | NPR3 | P17342 | 1/20 | 0.31 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967521 | 1.00 | SCN9A (0.35) | SCN9AFLT4KMT2AMEN1JAK2 | |
| SCHEMBL6961824 | 0.89 | PABPC1 (0.42) | SCN9AKMT2APABPC1NPR3 | |
| SCHEMBL6955844 | 0.89 | SCN9A (0.35) | SCN9AJAK2JAK3PTK2PABPC1 | |
| SCHEMBL6961818 | 0.89 | PABPC1 (0.42) | SCN9AKMT2APABPC1NPR3 | |
| SCHEMBL6967941 | 0.89 | TRPC3 (0.34) | KMT2AMEN1JAK2KCNH3 | |
| SCHEMBL7688088 | 0.88 | POLB (0.39) | SCN9AKMT2AMEN1PABPC1 | |
| SCHEMBL7688087 | 0.88 | POLB (0.39) | SCN9AKMT2AMEN1PABPC1 | |
| SCHEMBL6968925 | 0.88 | SCN9A (0.34) | SCN9APABPC1 | |
| SCHEMBL6962471 | 0.88 | JAK2 (0.33) | JAK2JAK3PTK2PABPC1 | |
| SCHEMBL6955835 | 0.87 | KLK7 (0.41) | SCN9APABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |