Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955844 | 0.94 | SCN9A (0.35) | SCN9APABPC1CACNA1BCCNT1CCNA2 | |
| SCHEMBL6968920 | 0.91 | KLK7 (0.42) | SCN9APABPC1CACNA1BKLK7KLK5 | |
| SCHEMBL6961824 | 0.91 | PABPC1 (0.42) | SCN9APABPC1 | |
| SCHEMBL6961818 | 0.91 | PABPC1 (0.42) | SCN9APABPC1 | |
| SCHEMBL6955835 | 0.89 | KLK7 (0.41) | SCN9APABPC1KLK7KLK5CCNT1 | |
| SCHEMBL6955840 | 0.89 | KLK7 (0.41) | SCN9APABPC1KLK7KLK5CCNT1 | |
| SCHEMBL7688087 | 0.89 | POLB (0.39) | SCN9APABPC1CACNA1BKLK7KLK5 | |
| SCHEMBL7688088 | 0.89 | POLB (0.39) | SCN9APABPC1CACNA1BKLK7KLK5 | |
| SCHEMBL6967521 | 0.88 | SCN9A (0.35) | SCN9APABPC1 | |
| SCHEMBL6967519 | 0.88 | SCN9A (0.35) | SCN9APABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |