Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.57 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976242 | 0.92 | FAAH (0.46) | FAAHCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL6976244 | 0.92 | FAAH (0.46) | FAAHCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL6961833 | 0.88 | FAAH (0.41) | FAAHCHRNB4CHRNA3CHRNB2CHRNB1 | |
| SCHEMBL6963235 | 0.84 | FAAH (0.40) | FAAHCHRNB2CHRNA4KCNH2MCHR1 | |
| SCHEMBL6963231 | 0.84 | FAAH (0.40) | FAAHCHRNB2CHRNA4KCNH2MCHR1 | |
| SCHEMBL8522230 | 0.84 | KCNH2 (0.39) | FAAHCHRNB2CHRNA4KCNH2MCHR1 | |
| SCHEMBL6958917 | 0.82 | CNR1 (0.43) | — | |
| SCHEMBL6958913 | 0.82 | CNR1 (0.43) | — | |
| SCHEMBL6968798 | 0.81 | SPHK1 (0.45) | MCHR1SPHK2SPHK1 | |
| SCHEMBL6968802 | 0.81 | SPHK1 (0.45) | MCHR1SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889032-A | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-30 | — | — | US | disclosed |