Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27860948 | 0.79 | CHRNA1 (0.48) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL6971681 | 0.78 | CA1 (0.44) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL28425450 | 0.72 | CA1 (0.52) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL11162269 | 0.71 | SLC6A2 (0.55) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL6448504 | 0.71 | KDM1A (0.54) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| 1,3-Dimethoxybenzene SCHEMBL9350 | 0.67 | ACHE (0.70) | CA1CA2CA7CA9ACHE | |
| 1,3-Dimethoxybenzene SCHEMBL901285 | 0.67 | ACHE (0.70) | CA1CA2CA7CA9ACHE | |
| SCHEMBL6841581 | 0.67 | KDM1A (0.54) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL22369878 | 0.67 | KDM1A (0.54) | KDM1ACA1CA2CA7CA9 | |
| SCHEMBL6446868 | 0.67 | SLC6A4 (0.50) | SLC6A2SLC6A3KDM1ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |