Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.30 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969885 | 0.83 | — | — | |
| SCHEMBL6969249 | 0.82 | DRD2 (0.30) | DRD2HTR2AHTR7HTR6HSP90AA1 | |
| SCHEMBL6969693 | 0.81 | VCP (0.38) | — | |
| SCHEMBL6961640 | 0.81 | MAPT (0.31) | — | |
| SCHEMBL8109935 | 0.81 | HSP90B1 (0.32) | DRD2HTR2AHTR7HTR6HSP90AA1 | |
| SCHEMBL6974005 | 0.80 | — | — | |
| SCHEMBL7082337 | 0.80 | LMNA (0.36) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL6974384 | 0.78 | HSP90B1 (0.34) | DRD2HTR2AHTR7HTR6HSP90AA1 | |
| SCHEMBL6958048 | 0.78 | HSP90B1 (0.33) | DRD2HTR2AHTR7HTR6HSP90AA1 | |
| SCHEMBL6974006 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |