Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963603 | 0.95 | KCNH3 (0.36) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL6958530 | 0.92 | TNF (0.38) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL6958401 | 0.91 | UBE2B (0.43) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL6955503 | 0.91 | MAPT (0.35) | MAPTRAB9AKMT2ANPC1OPRM1 | |
| SCHEMBL6967711 | 0.90 | TRPC3 (0.37) | MEN1KMT2AKDM4ETSHRMAPK1 | |
| SCHEMBL6957788 | 0.89 | TRPM8 (0.37) | MEN1KMT2ANPSR1JAK2JAK1 | |
| SCHEMBL6967410 | 0.88 | KCNH3 (0.34) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6967941 | 0.88 | TRPC3 (0.34) | MEN1KMT2AKDM4ETSHRMAPK1 | |
| SCHEMBL6958921 | 0.88 | DRD1 (0.36) | MAPTKMT2AKDM4ENPSR1TP53 | |
| SCHEMBL6968472 | 0.88 | NPSR1 (0.34) | MEN1KMT2AALDH1A1HSD17B10THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |