Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954449 | 0.94 | NOTUM (0.36) | KCNH3THRBSMN1; SMN2TRPC3TRPC6 | |
| SCHEMBL6962395 | 0.92 | GAA (0.36) | KCNH3THRBSMN1; SMN2TRPC3TRPC6 | |
| SCHEMBL6967711 | 0.92 | TRPC3 (0.37) | KCNH3THRBTRPC3TRPC6NPSR1 | |
| SCHEMBL6963630 | 0.91 | GAA (0.36) | KCNH3THRBSMN1; SMN2TRPC3TRPC6 | |
| SCHEMBL6967941 | 0.90 | TRPC3 (0.34) | KCNH3THRBSMN1; SMN2TRPC3TRPC6 | |
| SCHEMBL6963603 | 0.90 | KCNH3 (0.36) | KCNH3THRBSMN1; SMN2NPSR1KMT2A | |
| SCHEMBL6957770 | 0.89 | THRB (0.35) | KCNH3THRBTRPM8JAK2JAK1 | |
| Hydrochloric Acid SCHEMBL6961096 | 0.89 | KDM4E (0.34) | KCNH3THRBSMN1; SMN2TRPC3TRPC6 | |
| SCHEMBL6962206 | 0.88 | MAPT (0.36) | THRBSMN1; SMN2NPSR1KMT2AKDM4E | |
| SCHEMBL6970438 | 0.88 | GAA (0.36) | KCNH3THRBSMN1; SMN2NPSR1MARK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |
| EP-1015444-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998043968-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1998-10-08 | — | — | WO | disclosed |