Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962832 | 0.95 | NR1D1 (0.34) | NR1D1EGFRKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6961519 | 0.91 | KMT2A (0.33) | EGFRKMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL6961880 | 0.91 | KMT2A (0.38) | EGFRKMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL6970019 | 0.89 | SMN1; SMN2 (0.37) | EGFRKMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL6957761 | 0.87 | TP53 (0.40) | KMT2AMAPTSMN1; SMN2NPSR1HTR1A | |
| SCHEMBL6963254 | 0.87 | TP53 (0.33) | EGFRKMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL6966508 | 0.86 | KMT2A (0.37) | EGFRKMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL6962863 | 0.86 | KMT2A (0.38) | KMT2AMAPTSMN1; SMN2NPSR1KDM4E | |
| SCHEMBL6954411 | 0.86 | SMN1; SMN2 (0.39) | EGFRKMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL6961033 | 0.85 | SRD5A1 (0.36) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |