Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | HPGDS | O60760 | 12/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25308335 | 0.89 | ALOX15 (0.49) | MAOBHPGDSCYP4F2CYP4A11ALOX15 | |
| SCHEMBL30527598 | 0.89 | ALOX15 (0.49) | MAOBHPGDSCYP4F2CYP4A11ALOX15 | |
| SCHEMBL6960807 | 0.81 | HPGDS (0.48) | MAOBHPGDSALOX15HTTPSMD14 | |
| SCHEMBL2001821 | 0.81 | HPGDS (0.51) | MAOBHPGDSALOX15HTTPSMD14 | |
| SCHEMBL17221411 | 0.80 | MAOB (0.53) | MAOBHPGDSALOX15HTTPSMD14 | |
| SCHEMBL1043657 | 0.80 | HPGDS (0.52) | MAOBHPGDSALOX15HTTPSMD14 | |
| SCHEMBL7440151 | 0.79 | PTPN11 (0.53) | CYP4F2CYP4A11ALOX15HTT | |
| SCHEMBL30917343 | 0.79 | PTPN11 (0.53) | CYP4F2CYP4A11ALOX15HTT | |
| SCHEMBL3575601 | 0.78 | HPGDS (0.54) | MAOBHPGDSALOX15HTTPSMD14 | |
| SCHEMBL19021550 | 0.78 | HPGDS (0.74) | MAOBHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| CN-1071333-C | Quinoline derivative | NIPPON CHEMIPHAR CO (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1170411-A | Quinoline derivative | NIPPON CHEMIPHAR CO (JP) | 1998-01-14 | — | — | CN | disclosed |
| US-5693651-A | HYPOGLYCEMIC AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |