Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 7/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962919 | 0.81 | MAOB (0.51) | HPGDSMAOBALOX15HTTPSMD14 | |
| SCHEMBL6958945 | 0.79 | CRHBP (0.42) | KDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL3607026 | 0.78 | HDAC3 (0.58) | HDAC1HDAC3HDAC2NCOR2KDM4E | |
| SCHEMBL6958317 | 0.78 | CRHBP (0.40) | CFTRHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL18571617 | 0.76 | MAOB (0.67) | HPGDSMAOBHPGD | |
| SCHEMBL2031896 | 0.75 | ALOX15 (0.65) | HPGDSCFTRALOX15HTTPSMD14 | |
| SCHEMBL29505143 | 0.75 | ALOX15 (0.65) | HPGDSCFTRALOX15HTTPSMD14 | |
| SCHEMBL6960815 | 0.75 | HPGDS (0.47) | HPGDSMAOBALOX15HTTPSMD14 | |
| SCHEMBL12132268 | 0.73 | ALOX15 (0.49) | HPGDSCFTRALOX15HTTPSMD14 | |
| SCHEMBL17221411 | 0.73 | MAOB (0.53) | HPGDSMAOBALOX15HTTPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5693651-A | HYPOGLYCEMIC AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |