SCHEMBL6962941

SCHEMBL6962941

NC(=O)Cc1ccc(NCc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 8/20 0.64
FFAR4 Q5NUL3 2/20 0.61
HTT P42858 1/20 0.58
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA12 O43570 1/20 0.54
CA9 Q16790 1/20 0.54
ALDH1A1 P00352 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
HIF1A Q16665 1/20 0.54
RAB9A P51151 1/20 0.51
GFER P55789 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ACHE P22303 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27805772 0.88 FFAR1 (0.67) FFAR1FFAR4HIF1A
SCHEMBL28070143 0.87 MAPT (0.71) CA1CA2CA12CA9ALDH1A1
SCHEMBL11256418 0.86 MAPT (0.64) FFAR1HTTCA1CA2CA12
SCHEMBL5447986 0.86 FFAR1 (0.84) FFAR1FFAR4HTTCA1CA2
N-Benzylaniline SCHEMBL28146501 0.83 FFAR1 (0.62) FFAR1FFAR4HTTCA1CA2
SCHEMBL27805771 0.83 FFAR1 (0.64) FFAR1FFAR4HTTSMN1; SMN2
SCHEMBL30687012 0.82 GFER (0.54) FFAR1FFAR4HTTALDH1A1GFER
SCHEMBL30687017 0.82 FFAR1 (0.50) FFAR1ALDH1A1MEN1KMT2A
SCHEMBL25676 0.81 CES1 (0.64) CA2ALDH1A1HIF1AMEN1KMT2A
SCHEMBL30687019 0.81 CA1 (0.63) FFAR1CA1CA2CA12SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066023-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2024-02-29 US claimed
US-20210290615-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2021-09-23 US claimed
US-20200261441-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2020-08-20 US claimed
US-20200246328-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2020-08-06 US claimed
EP-0713483-B1 AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES ASTRAZENECA AB (SE) 2003-01-15 EP disclosed
US-6030985-A Amidine derivatives with nitric oxide synthetase activities ASTRA AKTIEBOLAG (SE) 2000-02-29 US disclosed
US-5807885-A Amidine derivatives with nitric oxide synthetase activities ASTRA AKTIEBOLAG (SE) 1998-09-15 US disclosed
WO-1995005363-A1 AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES ASTRA AKTIEBOLAG (SE) 1995-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200246328-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 FFAR1 4464/4885FFAR4 4055/4885HTT 2657/4885
US-20210290615-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition AHNAK, RECQL, NBAS FFAR1 4565/4885FFAR4 4278/4885HTT 2408/4885
US-20240066023-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition AHNAK, RECQL, NBAS FFAR1 4565/4885FFAR4 4278/4885HTT 2408/4885
US-20200261441-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 FFAR1 4464/4885FFAR4 4055/4885HTT 2657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.