Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | BLM | P54132 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962941 | 0.87 | FFAR1 (0.64) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL1395785 | 0.87 | PARP10 (0.68) | MAPTGAAPARP10RAB9AL3MBTL1 | |
| SCHEMBL27805772 | 0.85 | FFAR1 (0.67) | — | |
| SCHEMBL11838896 | 0.84 | MAPT (0.84) | MAPTMEN1GAABLMKMT2A | |
| SCHEMBL11253865 | 0.84 | MAPT (0.74) | MAPTMEN1GAABLMKMT2A | |
| SCHEMBL4667164 | 0.83 | MAPT (1.00) | MAPTMEN1GAABLMKMT2A | |
| SCHEMBL8082984 | 0.83 | MAPT (0.82) | MAPTMEN1GAABLMKMT2A | |
| SCHEMBL17602252 | 0.82 | MAOB (0.74) | MAPTMEN1GAABLMKMT2A | |
| SCHEMBL29245141 | 0.81 | CA1 (0.77) | MAPTMEN1GAABLMKMT2A | |
| SCHEMBL28790472 | 0.79 | FFAR1 (0.63) | MAPTMEN1GAAKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103739540-B | A kind of preparation method of bazedoxifene acetate intermediate | CHINA RESOURCES SAIKE PHARMACEUTICAL CO., LTD. (CN) | 2016-05-04 | — | — | CN | disclosed |