Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407901 | 1.00 | ANPEP (0.33) | ANPEPIDO1CYP2D6MEN1RECQL | |
| SCHEMBL1383876 | 0.78 | ANPEP (0.39) | ANPEPIDO1PLAU | |
| SCHEMBL9510934 | 0.78 | ANPEP (0.39) | ANPEP | |
| SCHEMBL4513001 | 0.73 | IDO1 (0.32) | IDO1PLAU | |
| SCHEMBL11004524 | 0.73 | ACHE (0.41) | IDO1 | |
| SCHEMBL5848345 | 0.73 | PLAU (0.39) | ANPEPIDO1PLAU | |
| SCHEMBL7472112 | 0.73 | PLAU (0.39) | ANPEPIDO1PLAU | |
| SCHEMBL4281029 | 0.71 | PNMT (0.35) | ANPEPMEN1KMT2A | |
| SCHEMBL8630503 | 0.70 | PRCP (0.37) | CYP2D6MEN1KMT2A | |
| SCHEMBL6326122 | 0.70 | ACHE (0.34) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057827-B1 | SPIROPIPERIDINE DERIVATIVES | SANKYO CO (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6511975-B1 | Exhibit antagonistic action against tachykinin receptors | SANKYO COMPANY, LIMITED (JP) | 2003-01-28 | — | — | US | disclosed |
| EP-1057827-A1 | SPIROPIPERIDINE DERIVATIVES | Sankyo Company Limited (JP) | 2000-12-06 | — | — | EP | disclosed |