SCHEMBL8630503

SCHEMBL8630503

[C]1c2ccccc2CC1c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRCP P42785 2/20 0.37
GAA P10253 2/20 0.36
MAPT P10636 1/20 0.36
SIGMAR1 Q99720 5/20 0.34
GRIN2B Q13224 1/20 0.34
NOS3 P29474 1/20 0.33
TSHR P16473 1/20 0.32
SLC18A3 Q16572 1/20 0.32
HTR2A P28223 2/20 0.32
HTR2C P28335 2/20 0.32
HTR2B P41595 2/20 0.32
HRH3 Q9Y5N1 2/20 0.32
CYP11B2 P19099 1/20 0.32
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
KMT2A Q03164 1/20 0.32
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31
KDM1A O60341 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1634692 0.80 CYP11B2 (0.41) PRCPGAASIGMAR1GRIN2BCYP11B2
SCHEMBL2083372 0.71 KDM1A (0.42) CYP2D6KDM1ACYP2C19
SCHEMBL7472112 0.70 PLAU (0.39) SIGMAR1HTR2AKDM1A
SCHEMBL4407901 0.70 ANPEP (0.33) MEN1CYP2D6KMT2A
SCHEMBL11004524 0.70 ACHE (0.41) NOS3TSHRMAOAMAOB
SCHEMBL4513001 0.70 IDO1 (0.32)
SCHEMBL5848345 0.70 PLAU (0.39) SIGMAR1HTR2AKDM1A
SCHEMBL6962983 0.70 ANPEP (0.33) MEN1CYP2D6KMT2A
SCHEMBL7471523 0.67 ALDH1A1 (0.34) MAPTHTR2AHTR2CHTR2BHRH3
SCHEMBL577506 0.67 CYP19A1 (0.41) GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0860744-A1 Electrophotographic elements exhibiting reduced numbers of black spots in discharge area development systems EASTMAN KODAK COMPANY (US) 1998-08-26 EP claimed
US-5780192-A PHOTOCONDUCTIVE LAYER COMPRISING A BLENDS OF POLYESTER COPOLYMERS; PHOTOSTABILITY, PHOTOSENSITIVITY; DIGITAL PRINTER, DIGITAL COPIER EASTMAN KODAK COMPANY (US) 1998-07-14 US claimed
EP-0008828-B1 PHOTOCROSSLINKABLE, HIGH-TEMPERATURE-RESISTANT POLYMERS AND THEIR USE IN COLOR IMAGING DEVICES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-07-20 EP claimed
EP-0008828-A2 Photocrosslinkable, high-temperature-resistant polymers and their use in color imaging devices EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-03-19 EP claimed
EP-0860744-A1 Electrophotographic elements exhibiting reduced numbers of black spots in discharge area development systems EASTMAN KODAK COMPANY (US) 1998-08-26 EP disclosed
US-5780192-A PHOTOCONDUCTIVE LAYER COMPRISING A BLENDS OF POLYESTER COPOLYMERS; PHOTOSTABILITY, PHOTOSENSITIVITY; DIGITAL PRINTER, DIGITAL COPIER EASTMAN KODAK COMPANY (US) 1998-07-14 US disclosed
EP-0008828-B1 PHOTOCROSSLINKABLE, HIGH-TEMPERATURE-RESISTANT POLYMERS AND THEIR USE IN COLOR IMAGING DEVICES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-07-20 EP disclosed