⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961360 | 0.97 | — | — | |
| SCHEMBL6965985 | 0.93 | — | — | |
| SCHEMBL6965989 | 0.83 | CYP19A1 (0.32) | — | |
| SCHEMBL6963452 | 0.82 | CHRNB2 (0.43) | — | |
| SCHEMBL6958774 | 0.82 | TACR1 (0.36) | — | |
| SCHEMBL6965541 | 0.82 | NAAA (0.42) | — | |
| SCHEMBL6957912 | 0.81 | HTR2A (0.35) | — | |
| SCHEMBL6957860 | 0.80 | CNR1 (0.35) | — | |
| SCHEMBL6956374 | 0.80 | P2RX7 (0.36) | — | |
| SCHEMBL6958250 | 0.79 | TACR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610721-B2 | Imidazo heterocyclic compounds | NOVO NORDISK A/S (DK) | 2003-08-26 | — | — | US | disclosed |
| EP-1268483-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| US-20010049385-A1 | Imidazo heterocyclic compounds | HIGH POINT PHARMACEUTICALS, LLC | 2001-12-06 | — | — | US | disclosed |
| WO-2001068651-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |