Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | STAT5B | P51692 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31172517 | 0.80 | HDAC1 (0.49) | LMNANOTUMP4HBMEN1KMT2A | |
| SCHEMBL16347649 | 0.79 | TP53 (0.61) | TP53LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL3577577 | 0.78 | NOTUM (0.57) | TP53LMNANOTUMP4HBMEN1 | |
| SCHEMBL6171032 | 0.74 | SMN1; SMN2 (0.53) | NOTUMP4HBMEN1KMT2ACYP1A2 | |
| SCHEMBL1040017 | 0.73 | NOTUM (0.55) | TP53LMNANOTUMP4HBMEN1 | |
| SCHEMBL29975942 | 0.73 | NOTUM (0.55) | TP53LMNANOTUMP4HBMEN1 | |
| SCHEMBL30848162 | 0.73 | P4HB (0.66) | TP53LMNANOTUMP4HBMEN1 | |
| SCHEMBL18973337 | 0.73 | P4HB (0.66) | TP53LMNANOTUMP4HBMEN1 | |
| SCHEMBL17010776 | 0.72 | LOXL2 (0.54) | TP53LMNANOTUMP4HBMEN1 | |
| SCHEMBL31063216 | 0.72 | NOTUM (0.54) | TP53LMNANOTUMP4HBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| US-6350774-B1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2002-02-26 | — | — | US | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |