Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636898 | 0.84 | OPRM1 (0.50) | OPRM1OPRD1OPRK1CACNA1C | |
| Oxalic Acid SCHEMBL9372788 | 0.81 | OPRD1 (0.37) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL29174216 | 0.81 | OPRM1 (0.66) | OPRM1OPRD1OPRK1CACNA1C | |
| Oxalic Acid SCHEMBL6045565 | 0.79 | OPRM1 (0.55) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL6963035 | 0.78 | OPRM1 (0.68) | OPRM1OPRD1OPRK1 | |
| Oxalic Acid SCHEMBL6045520 | 0.78 | OPRM1 (0.54) | OPRM1OPRD1OPRK1 | |
| SCHEMBL8097591 | 0.74 | OPRL1 (0.58) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10460790 | 0.73 | OPRD1 (0.71) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL10398382 | 0.73 | OPRM1 (0.71) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL10688179 | 0.72 | OPRM1 (0.70) | OPRM1OPRD1OPRK1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869791-B1 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2003-05-07 | — | — | EP | disclosed |