Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | CCR3 | P51677 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955503 | 0.92 | MAPT (0.35) | TYK2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6963603 | 0.90 | KCNH3 (0.36) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6957788 | 0.90 | TRPM8 (0.37) | TRPM8JAK2TYK2JAK1 | |
| SCHEMBL6962206 | 0.87 | MAPT (0.36) | JAK2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6967711 | 0.85 | TRPC3 (0.37) | TRPM8JAK2KDM4EJAK1LMNA | |
| SCHEMBL6968472 | 0.84 | NPSR1 (0.34) | GRM5CDC7JAK2TYK2SMN1; SMN2 | |
| SCHEMBL6958530 | 0.84 | TNF (0.38) | JAK2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6962446 | 0.84 | HRH3 (0.35) | JAK2KDM4EJAK1LMNAMAPT | |
| SCHEMBL6958401 | 0.83 | UBE2B (0.43) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6967941 | 0.83 | TRPC3 (0.34) | TRPM8JAK2KDM4ESMN1; SMN2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |