Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963573 | 0.87 | KDM4E (0.63) | MAPTGAAKDM4EALDH1A1TP53 | |
| SCHEMBL8661913 | 0.87 | MAOA (0.56) | MAPTGAAKDM4EALDH1A1TP53 | |
| SCHEMBL6965667 | 0.86 | KMT2A (0.51) | MAPTGAAKDM4EALDH1A1TP53 | |
| SCHEMBL6966261 | 0.85 | MEN1 (0.55) | MAPTGAAKDM4EALDH1A1MAOB | |
| SCHEMBL8642829 | 0.82 | KMT2A (0.53) | MAPTGAAKDM4EALDH1A1MAOB | |
| SCHEMBL8496984 | 0.80 | KDM4E (0.62) | MAPTGAAKDM4EALDH1A1TP53 | |
| SCHEMBL6955199 | 0.78 | KMT2A (0.51) | MAPTGAAKDM4EALDH1A1MAOB | |
| SCHEMBL6966665 | 0.78 | MAOB (0.47) | MAPTKDM4EALDH1A1MAOBNPC1 | |
| SCHEMBL12501713 | 0.77 | KMT2A (0.78) | MAPTKDM4EALDH1A1TP53MAOB | |
| Hydrochloric Acid SCHEMBL7221783 | 0.75 | HIF1A (0.56) | KDM4EALDH1A1TP53MAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787723-B1 | CYCLOPROPACHROMENECARBOXYLATE DERIVATIVES | SUNTORY LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-5843988-A | Cyclopropachromencarboxylic acid derivatives | SUNTORY LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0787723-A1 | CYCLOPROPACHROMENECARBOXYLATE DERIVATIVES | SUNTORY LIMITED (JP) | 1997-08-06 | — | — | EP | disclosed |