Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963159 | 0.82 | MAPT (0.57) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL6963573 | 0.81 | KDM4E (0.63) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL6891384 | 0.81 | KMT2A (0.67) | KMT2AMEN1ALDH1A1MAPTMAOB | |
| SCHEMBL6966261 | 0.79 | MEN1 (0.55) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL6955199 | 0.77 | KMT2A (0.51) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL6965667 | 0.76 | KMT2A (0.51) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL8641561 | 0.74 | KMT2A (0.68) | KMT2AMEN1ALDH1A1MAPTGAA | |
| Hydrochloric Acid SCHEMBL7221783 | 0.74 | HIF1A (0.56) | KMT2AMEN1ALDH1A1MAOBHTT | |
| SCHEMBL8661913 | 0.72 | MAOA (0.56) | KMT2AALDH1A1MAPTGAAKDM4E | |
| SCHEMBL6966665 | 0.70 | MAOB (0.47) | ALDH1A1MAPTMAOBKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625522-B1 | Benzopyran derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5741784-A | ADMINISTERING TO TREAT METABOLIC BONE DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-21 | — | — | US | disclosed |
| US-5580863-A | TREATMENT OF OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0625522-A1 | Benzopyran derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |