Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963159 | 0.86 | MAPT (0.57) | KMT2AMEN1HTTMAPTGAA | |
| SCHEMBL6963573 | 0.82 | KDM4E (0.63) | KMT2AMEN1HTTMAPTGAA | |
| SCHEMBL6966261 | 0.78 | MEN1 (0.55) | KMT2AMEN1HTTMAPTGAA | |
| SCHEMBL6952512 | 0.78 | KMT2A (0.71) | KMT2AMEN1HTTDUSP3PTPN11 | |
| SCHEMBL8661913 | 0.78 | MAOA (0.56) | KMT2AMAPTGAAKDM4EALDH1A1 | |
| SCHEMBL8642829 | 0.76 | KMT2A (0.53) | KMT2AMEN1HTTMAPTGAA | |
| SCHEMBL28639941 | 0.74 | KMT2A (0.69) | KMT2AMEN1HTTDUSP3PTPN11 | |
| SCHEMBL29923968 | 0.74 | KMT2A (0.69) | KMT2AMEN1HTTDUSP3PTPN11 | |
| SCHEMBL6960727 | 0.72 | MEN1 (0.54) | KMT2AMEN1HTTMAPTGAA | |
| SCHEMBL9528168 | 0.72 | LCK (0.78) | KMT2AMEN1MAPTKDM4ECSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787723-B1 | CYCLOPROPACHROMENECARBOXYLATE DERIVATIVES | SUNTORY LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-5843988-A | Cyclopropachromencarboxylic acid derivatives | SUNTORY LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0787723-A1 | CYCLOPROPACHROMENECARBOXYLATE DERIVATIVES | SUNTORY LIMITED (JP) | 1997-08-06 | — | — | EP | disclosed |