Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | BID | P55957 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.34 |
| ▸ | BCL2L10 | Q9HD36 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964322 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTRAB9ANPC1 | |
| SCHEMBL6958137 | 0.95 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTRAB9ANPC1 | |
| SCHEMBL6958132 | 0.95 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTRAB9ANPC1 | |
| SCHEMBL6967088 | 0.91 | SCN9A (0.34) | ALDH1A1KDM4EMAPTRAB9ANPC1 | |
| SCHEMBL6967090 | 0.91 | SCN9A (0.34) | ALDH1A1KDM4EMAPTRAB9ANPC1 | |
| SCHEMBL6963190 | 0.90 | SCN9A (0.39) | ALDH1A1KDM4EMAPTPOLBTSHR | |
| SCHEMBL6963186 | 0.90 | SCN9A (0.39) | ALDH1A1KDM4EMAPTPOLBTSHR | |
| SCHEMBL6965678 | 0.89 | PABPC1 (0.41) | EPHX2SCN9A | |
| SCHEMBL6965676 | 0.89 | PABPC1 (0.41) | EPHX2SCN9A | |
| SCHEMBL6963915 | 0.88 | SCN9A (0.36) | ALDH1A1KDM4EMAPTTSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |