Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102772 | 0.86 | CA1 (0.69) | LMNAHPGDCTRB1CA1CA2 | |
| SCHEMBL18232126 | 0.86 | CA1 (0.69) | LMNAHPGDCTRB1CA1CA2 | |
| SCHEMBL1649573 | 0.86 | CA1 (0.69) | LMNAHPGDCTRB1CA1CA2 | |
| SCHEMBL14595547 | 0.85 | LMNA (0.56) | LMNAHPGDCTRB1CA1CA2 | |
| SCHEMBL27997270 | 0.83 | LMNA (0.59) | LMNAHPGDCTRB1CA1CA2 | |
| SCHEMBL9848833 | 0.83 | ALDH1A1 (0.55) | LMNAHPGDCTRB1CA1CA2 | |
| SCHEMBL18220893 | 0.83 | LMNA (0.54) | LMNAHPGDCTRB1CA1CA2 | |
| Benzoic Acid SCHEMBL6534685 | 0.81 | CA1 (0.63) | LMNAHPGDCTRB1CA1CA2 | |
| SCHEMBL25366914 | 0.80 | TACR3 (0.59) | LMNAHPGDCTRB1S1PR3ALDH1A1 | |
| SCHEMBL4444765 | 0.80 | S1PR3 (0.56) | LMNAHPGDCTRB1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |