Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961311 | 0.90 | TSHR (0.49) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL3029392 | 0.82 | TSHR (0.50) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6973564 | 0.81 | PSEN1 (0.48) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6971657 | 0.81 | NPC1 (0.47) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6969247 | 0.81 | ALDH1A1 (0.57) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6190803 | 0.77 | RAB9A (0.56) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6530208 | 0.77 | SYK (0.52) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6529620 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6961781 | 0.75 | SMN1; SMN2 (0.43) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL9177839 | 0.75 | NPC1 (0.53) | ALDH1A1NPC1TP53MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181288-B1 | BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT | UPJOHN CO (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6387896-B1 | GRAMNEGATIVE, GRAMPOSITVE BACTERIA | PHARMACIA & UPJOHN CO. | 2002-05-14 | — | — | US | disclosed |