Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29352033 | 1.00 | KDM4E (0.53) | KDM4EGAAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6963866 | 0.90 | SMN1; SMN2 (0.56) | KDM4EGAAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6958741 | 0.86 | LMNA (0.62) | KDM4EGAAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6963378 | 0.85 | SMN1; SMN2 (0.53) | KDM4EGAAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9579768 | 0.84 | NPC1 (0.44) | KDM4EGAAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL29355435 | 0.83 | ALDH1A1 (0.54) | KDM4EGAAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6964163 | 0.83 | ALDH1A1 (0.54) | KDM4EGAAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6965016 | 0.83 | NPC1 (0.56) | KDM4EGAAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL1520344 | 0.82 | SMN1; SMN2 (0.71) | KDM4EGAAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6957303 | 0.81 | KDM4E (0.50) | KDM4EGAAMAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |