SCHEMBL6958741

SCHEMBL6958741

COc1ccc(CCNC(=S)Nc2nccs2)cc1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 10/20 0.62
ALDH1A1 P00352 3/20 0.62
KDM4E B2RXH2 2/20 0.58
ALOX12 P18054 5/20 0.56
MAPT P10636 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.55
RAB9A P51151 3/20 0.54
NPC1 O15118 2/20 0.54
PKM P14618 1/20 0.54
GAA P10253 1/20 0.53
HTT P42858 1/20 0.53
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6963302 0.86 KDM4E (0.53) LMNAKDM4EMAPTSMN1; SMN2NPC1
SCHEMBL29352033 0.86 KDM4E (0.53) LMNAKDM4EMAPTSMN1; SMN2NPC1
SCHEMBL6284717 0.86 KDM4E (0.57) LMNAALDH1A1KDM4ESMN1; SMN2RAB9A
SCHEMBL6280318 0.85 SMN1; SMN2 (0.55) LMNAALDH1A1KDM4EALOX12MAPT
SCHEMBL29356264 0.84 GAA (0.63) LMNAALDH1A1KDM4EALOX12MAPT
SCHEMBL1520344 0.83 SMN1; SMN2 (0.71) LMNAALDH1A1KDM4EALOX12MAPT
SCHEMBL6953591 0.83 KDM4E (0.53) LMNAALDH1A1KDM4EMAPTSMN1; SMN2
SCHEMBL6957303 0.83 KDM4E (0.50) LMNAALDH1A1KDM4EALOX12MAPT
SCHEMBL8683561 0.81 KDM4E (0.67) LMNAALDH1A1KDM4EALOX12MAPT
SCHEMBL6954481 0.80 KDM4E (0.44) LMNAALDH1A1KDM4EMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240251654-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2024-07-25 US claimed
CN-118103340-A Method for manufacturing medical injection device and medical injection device manufactured by same 斯特瓦纳托集团有限公司 2024-05-28 CN claimed
US-12622947-B2 Pharmaceutical composition for treating levodopa-induced dyskinesia or for suppressing progression thereof PEPTRON, INC. (KR) 2026-05-12 US disclosed
EP-4005587-B1 PHARMACEUTICAL COMPOSITION FOR TREATING LEVODOPA-INDUCED DYSKINESIA OR FOR SUPPRESSING PROGRESSION THEREOF PEPTRON INC (KR) 2026-03-18 EP disclosed
US-20250333645-A1 [2,2]PARACYCLOPHANE-BASED METAL (II) COMPLEXES, ELECTRONIC DEVICES, APPARATUS, AND USE THEREOF ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2025-10-30 US disclosed
EP-4640691-A1 [2,2]PARACYCLOPHANE-BASED METAL (II) COMPLEXES, ELECTRONIC DEVICES, APPARATUS, AND USE THEREOF Zhejiang Huaxian Photoelectricity Technology Co., Ltd (CN) 2025-10-29 EP disclosed
WO-2025202284-A1 GLP-1R ANTAGONISTS FOR THE TREATMENT OF CANCER FIORINA PAOLO (IT) 2025-10-02 WO disclosed
EP-4623928-A1 GLP-1R ANTAGONISTS FOR THE TREATMENT OF CANCER Fiorina, Paolo (IT) 2025-10-01 EP disclosed
US-20250295587-A1 COMPLEX LIPID NANOPARTICLES ENCAPSULATING POLYPEPTIDES AND USES THEREOF SAIL BIOMEDICINES, INC. 2025-09-25 US disclosed
US-20250134895-A1 METHODS AND COMPOSITIONS FOR TREATING ALPHA-SYNUCLEIN-MEDIATED NEURODEGENERATION UNIVERSITY HEALTH NETWORK (CA) 2025-05-01 US disclosed
US-20240408312-A1 METHOD OF MANUFACTURING A MEDICAL INJECTION DEVICE AND MEDICAL INJECTION DEVICE THUS OBTAINED STEVANTO GROUP S.P.A. (IT) 2024-12-12 US disclosed
EP-4005587-A1 PHARMACEUTICAL COMPOSITION FOR TREATING LEVODOPA-INDUCED DYSKINESIA OR FOR SUPPRESSING PROGRESSION THEREOF Peptron, Inc. (KR) 2022-06-01 EP disclosed
US-20220152139-A1 PLANT MESSENGER PACKS ENCAPSULATING POLYPEPTIDES AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2022-05-19 US disclosed
CN-114206374-A Pharmaceutical composition for treating levodopa-induced dyskinesia or for inhibiting progression thereof 佩特通公司 2022-03-18 CN disclosed
US-11230599-B2 Tumor mutational load MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-01-25 US disclosed
EP-0540143-B1 Compounds and methods for inhibition of HIV and related viruses MEDIVIR AB (SE) 2003-02-05 EP disclosed
US-5714503-A Compounds and methods for inhibition of HIV and related viruses MEDIVIR AB (SE) 1998-02-03 US disclosed
US-5593993-A VIRICIDES FOR HTLV TREATMENT OF AIDS MEDIVIR AB (SE) 1997-01-14 US disclosed
EP-0540143-A2 Compounds and methods for inhibition of HIV and related viruses Medivir Aktiebolag (SE) 1993-05-05 EP disclosed
WO-1993003022-A1 COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES MEDIVIR AB (SE) 1993-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250134895-A1 METHODS AND COMPOSITIONS FOR TREATING ALPHA-SYNUCLEIN-MEDIATED NEURODEGENERATION SNCA, SAMHD1, MAPT LMNA 576/4885ALDH1A1 1312/4885KDM4E 4222/4885
US-20240251654-A1 ORGANIC ELECTROLUMINESCENT DEVICE LEF1, EFNA1, EML4 LMNA 3318/4885ALDH1A1 131/4885KDM4E 2782/4885
US-20250333645-A1 [2,2]PARACYCLOPHANE-BASED METAL (II) COMPLEXES, ELECTRONIC DEVICES, APPARATUS, AND USE THEREOF OCIAD2, CCND2, OCIAD1 LMNA 3355/4885ALDH1A1 1615/4885KDM4E 4026/4885
US-12622947-B2 Pharmaceutical composition for treating levodopa-induced dyskinesia or for suppressing progression thereof GLP1R, GIPR, NPY1R LMNA 2227/4885ALDH1A1 3414/4885KDM4E 1042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.