Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 12/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358989 | 0.92 | LTA4H (0.49) | HRH3LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL7351952 | 0.90 | LTA4H (0.47) | HRH3HRH1LTA4HPSMB1PSMB5 | |
| SCHEMBL6969448 | 0.86 | LTA4H (0.50) | HRH3HRH1LTA4HPSMB1PSMB5 | |
| SCHEMBL6956973 | 0.85 | LTA4H (0.49) | HRH3HRH1LTA4HPSMB1PSMB5 | |
| SCHEMBL6961402 | 0.85 | LTA4H (0.48) | HRH3HRH1LTA4HPSMB1PSMB5 | |
| SCHEMBL7447035 | 0.84 | PSMB1 (0.64) | HRH3HRH1LTA4HPSMB1PSMB5 | |
| SCHEMBL6957263 | 0.83 | ACACB (0.45) | HRH3HRH1LTA4HPSMB1PSMB5 | |
| SCHEMBL7348634 | 0.82 | PSMB1 (0.55) | HRH3LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL6963616 | 0.82 | LTA4H (0.52) | HRH3HRH1LTA4HPSMB1PSMB5 | |
| SCHEMBL7349031 | 0.81 | LTA4H (0.49) | HRH3LTA4HPSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |