Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | PHGDH | O43175 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966490 | 0.91 | KMT2A (0.48) | MEN1KMT2APOLBCYP3A4CYP2C19 | |
| SCHEMBL6955540 | 0.89 | PHGDH (0.49) | MEN1KMT2APOLBCYP3A4CYP2C19 | |
| SCHEMBL6783848 | 0.88 | KMT2A (0.63) | MEN1KMT2APOLBCYP3A4CYP2C19 | |
| SCHEMBL6965253 | 0.88 | RBP4 (0.49) | KMT2APOLBNPC1LMNAGAA | |
| SCHEMBL6961151 | 0.82 | PHGDH (0.55) | MEN1KMT2APOLBCYP3A4CYP2C19 | |
| SCHEMBL6964180 | 0.81 | KMT2A (0.55) | MEN1KMT2APOLBCYP3A4CYP2C19 | |
| SCHEMBL6960712 | 0.78 | RBP4 (0.47) | MEN1KMT2APOLBLMNAGAA | |
| SCHEMBL6786898 | 0.78 | CYP3A4 (0.55) | MEN1KMT2APOLBCYP3A4CYP2C19 | |
| SCHEMBL6780561 | 0.77 | MEN1 (0.73) | MEN1KMT2APOLBCYP3A4CYP2C19 | |
| SCHEMBL6782760 | 0.77 | CYP3A4 (0.66) | MEN1KMT2APOLBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |