⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480174 | 0.83 | — | — | |
| SCHEMBL3186107 | 0.81 | — | — | |
| SCHEMBL1630761 | 0.77 | CHRNB2 (0.44) | — | |
| SCHEMBL1630764 | 0.77 | CHRNB2 (0.44) | — | |
| SCHEMBL2486077 | 0.77 | CHRNB2 (0.44) | — | |
| SCHEMBL5014594 | 0.74 | — | — | |
| SCHEMBL199619 | 0.74 | — | — | |
| SCHEMBL2845882 | 0.74 | — | — | |
| SCHEMBL11317644 | 0.74 | — | — | |
| SCHEMBL14300718 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882041-B1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2003-03-26 | — | — | EP | claimed |
| US-6069145-A | AGAINST ANTIBIOTIC RESISTANT BACTERIA | ZENECA LIMITED (GB) | 2000-05-30 | — | — | US | claimed |
| EP-0882041-B1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2003-03-26 | — | — | EP | disclosed |
| US-6069145-A | AGAINST ANTIBIOTIC RESISTANT BACTERIA | ZENECA LIMITED (GB) | 2000-05-30 | — | — | US | disclosed |
| EP-0882041-A1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AstraZeneca AB (SE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997027188-A1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 1997-07-31 | — | — | WO | disclosed |