⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963893 | 0.74 | — | — | |
| SCHEMBL1630764 | 0.74 | CHRNB2 (0.44) | — | |
| SCHEMBL1630761 | 0.74 | CHRNB2 (0.44) | — | |
| SCHEMBL2486077 | 0.74 | CHRNB2 (0.44) | — | |
| SCHEMBL6629418 | 0.73 | — | — | |
| SCHEMBL2845882 | 0.71 | — | — | |
| SCHEMBL11317644 | 0.71 | — | — | |
| SCHEMBL199619 | 0.71 | — | — | |
| SCHEMBL4354008 | 0.69 | TSHR (0.50) | — | |
| SCHEMBL1039978 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992349-B1 | CGRP antagonists, their preparation and use as a medicament | BOEHRINGER INGELHEIM INT (DE) | 2013-07-31 | — | — | EP | claimed |
| WO-1998031380-A1 | PHALLOIDIN DERIVATIVES AND ANALOGS TO TREAT CONGESTIVE HEART FAILURE | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1998-07-23 | — | — | WO | claimed |
| EP-1992349-A1 | CGRP antagonists, their preparation and use as a medicament | Boehringer Ingelheim International GmbH (DE) | 2008-11-19 | — | — | EP | disclosed |
| CN-1252066-C | Pyridazine-3-one derivatives, their use, and intermediate preparing them | SUMITOMO CHEMICAL CO (JP) | 2006-04-19 | — | — | CN | disclosed |
| CN-1491949-A | Pyridazine-3-one derivatives, their use, and intermediate preparing them | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-04-28 | — | — | CN | disclosed |
| CN-1117083-C | Pyridazin-3-one derivatives, their use, and intermediates for their preparation | SUMITOMO CHEMICAL CO (JP) | 2003-08-06 | — | — | CN | disclosed |
| CN-1202157-A | Pyridazin-3-one derivatives, their use, and intermediates for their preparation | SUMITOMO CHEMICAL CO (JP) | 1998-12-16 | — | — | CN | disclosed |