Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696395 | 0.87 | ALDH1A1 (0.41) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL697738 | 0.85 | ALDH1A1 (0.53) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL28059255 | 0.83 | ALDH1A1 (0.51) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL20548928 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2ACYP2D6CYP2C19LMNA | |
| SCHEMBL29700441 | 0.78 | ALOX15 (0.45) | CYP2C9MEN1KMT2ACYP2C19TSHR | |
| SCHEMBL28794540 | 0.78 | ALOX15 (0.45) | CYP2C9MEN1KMT2ACYP2C19TSHR | |
| SCHEMBL11795787 | 0.78 | CYP2C9 (0.49) | CYP2C9MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL14889180 | 0.76 | ALDH1A1 (0.54) | MEN1KMT2ACYP2D6CYP2C19LMNA | |
| SCHEMBL28775846 | 0.74 | CES2 (0.59) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL247590 | 0.74 | CES2 (0.59) | MEN1KMT2ALMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423211-B1 | PROCESSES FOR PRODUCING (1S,6S)- OR (1R,6R)-CIS-2,8-DIAZABICYCLO[4.3.0]NONANE AND INTERMEDIATE THEREOF | KANEKA CORP (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-2423211-A1 | PROCESSES FOR PRODUCING (1S,6S)- OR (1R,6R)-CIS-2,8-DIAZABICYCLO[4.3.0]NONANE AND INTERMEDIATE THEREOF | Kaneka Corporation (JP) | 2012-02-29 | — | — | EP | disclosed |