Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17387532 | 1.00 | L3MBTL1 (0.39) | L3MBTL1CHRM1FAAHMGLLPARP1 | |
| SCHEMBL3941458 | 0.81 | GPR119 (0.51) | GPR119USP30 | |
| SCHEMBL12546284 | 0.81 | GPR119 (0.51) | GPR119USP30 | |
| SCHEMBL3699887 | 0.81 | GPR119 (0.51) | GPR119USP30 | |
| SCHEMBL12306324 | 0.81 | GPR119 (0.51) | GPR119USP30 | |
| Bromide SCHEMBL2672194 | 0.79 | FAAH (0.41) | L3MBTL1CHRM1FAAHMGLLPARP1 | |
| Bromide SCHEMBL6962165 | 0.79 | FAAH (0.41) | L3MBTL1CHRM1FAAHMGLLPARP1 | |
| Bromide SCHEMBL2460258 | 0.79 | FAAH (0.41) | L3MBTL1CHRM1FAAHMGLLPARP1 | |
| Bromide SCHEMBL6962170 | 0.79 | FAAH (0.41) | L3MBTL1CHRM1FAAHMGLLPARP1 | |
| Bromide SCHEMBL3237328 | 0.79 | FAAH (0.41) | L3MBTL1CHRM1FAAHMGLLPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849269-B9 | Vinyl pyrrolidine cephalosporins with basic substituents | BASILEA PHARMACEUTICA AG (CH) | 2003-03-05 | — | — | EP | claimed |
| EP-0849269-B1 | Vinyl pyrrolidine cephalosporins with basic substituents | BASILEA PHARMACEUTICA AG (CH) | 2002-07-10 | — | — | EP | claimed |