Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67251 | 0.85 | CYP19A1 (0.41) | CNR1CNR2CYP19A1MEN1KMT2A | |
| SCHEMBL21855589 | 0.80 | CYP19A1 (0.45) | CNR1CNR2POLBCYP19A1ALDH1A1 | |
| SCHEMBL6963246 | 0.78 | SERPINH1 (0.39) | CNR1CNR2CYP19A1ALDH1A1MAOB | |
| SCHEMBL20495153 | 0.76 | HSPB1 (0.53) | HSPB1L3MBTL1POLBKCNJ1KCNH2 | |
| SCHEMBL66024 | 0.75 | SCN5A (0.44) | CNR1CNR2CYP19A1SMN1; SMN2RAB9A | |
| SCHEMBL536 | 0.74 | HSPB1 (0.75) | HSPB1POLBKCNJ1KCNH2ALDH1A1 | |
| SCHEMBL7026994 | 0.74 | HSPB1 (0.75) | HSPB1POLBKCNJ1KCNH2ALDH1A1 | |
| SCHEMBL66945 | 0.74 | SCN5A (0.43) | CNR1CNR2CYP19A1RAB9ALMNA | |
| SCHEMBL6683868 | 0.73 | MAPT (0.46) | L3MBTL1KCNJ1KCNH2ALDH1A1NPC1 | |
| Formic Acid SCHEMBL27530791 | 0.73 | HSPB1 (0.62) | HSPB1POLBKCNJ1KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339694-A1 | SUBSTITUTED 2-PHENYLAMINOIMIDAZOLINE PHENYL KETONE DERIVATIVES AS IP ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002040453-A1 | SUBSTITUTED 2-PHENYLAMINOIMIDAZOLINE PHENYL KETONE DERIVATIVES AS IP ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-05-23 | — | — | WO | disclosed |