Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINH1 | P50454 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67251 | 0.91 | CYP19A1 (0.41) | CNR1CNR2CACNA1BCYP19A1LMNA | |
| SCHEMBL21855589 | 0.86 | CYP19A1 (0.45) | CNR1CNR2CACNA1BCYP19A1LMNA | |
| SCHEMBL6962007 | 0.82 | SERPINH1 (0.41) | SERPINH1CNR1CNR2CACNA1BLMNA | |
| SCHEMBL66024 | 0.80 | SCN5A (0.44) | CNR1CNR2CACNA1BCYP19A1LMNA | |
| SCHEMBL66945 | 0.79 | SCN5A (0.43) | CNR1CNR2CACNA1BCYP19A1LMNA | |
| SCHEMBL6963985 | 0.78 | HSPB1 (0.46) | CNR1CNR2CYP19A1LMNAHTT | |
| SCHEMBL7235718 | 0.73 | HRH1 (0.50) | CNR1CNR2LMNAHTTGPR55 | |
| SCHEMBL5586175 | 0.73 | IDO1 (0.32) | LMNAHTTMEN1KMT2ATDP1 | |
| SCHEMBL26109029 | 0.73 | IDO1 (0.32) | CYP19A1LMNAHTTMEN1KMT2A | |
| SCHEMBL13619654 | 0.73 | AOC3 (0.44) | LMNANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339694-A1 | SUBSTITUTED 2-PHENYLAMINOIMIDAZOLINE PHENYL KETONE DERIVATIVES AS IP ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002040453-A1 | SUBSTITUTED 2-PHENYLAMINOIMIDAZOLINE PHENYL KETONE DERIVATIVES AS IP ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-05-23 | — | — | WO | disclosed |