SCHEMBL536

SCHEMBL536

O=[N+]([O-])c1ccc(F)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPB1 P04792 4/20 0.75
POLB P06746 1/20 0.67
ALDH1A1 P00352 4/20 0.56
ACHE P22303 1/20 0.56
HSD17B10 Q99714 1/20 0.56
KCNJ1 P48048 1/20 0.56
KCNH2 Q12809 1/20 0.56
LMNA P02545 2/20 0.55
MAOA P21397 1/20 0.55
MAOB P27338 1/20 0.55
MEN1 O00255 2/20 0.53
ALOX12 P18054 2/20 0.53
KMT2A Q03164 2/20 0.53
GAA P10253 2/20 0.53
MAPT P10636 1/20 0.53
PKM P14618 1/20 0.53
HPGD P15428 1/20 0.53
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TDP1 Q9NUW8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7026994 1.00 HSPB1 (0.75) HSPB1POLBALDH1A1ACHEHSD17B10
SCHEMBL28001935 0.97 HSPB1 (0.72) HSPB1POLBALDH1A1ACHEHSD17B10
Water SCHEMBL28147677 0.97 HSPB1 (0.72) HSPB1POLBALDH1A1ACHEHSD17B10
Fluoride SCHEMBL4551986 0.97 HSPB1 (0.72) HSPB1POLBALDH1A1ACHEHSD17B10
Fluoride SCHEMBL4551988 0.97 HSPB1 (0.72) HSPB1POLBALDH1A1ACHEHSD17B10
Ethylene SCHEMBL27864908 0.95 HSPB1 (0.69) HSPB1POLBALDH1A1ACHEHSD17B10
Formaldehyde SCHEMBL28237406 0.95 HSPB1 (0.69) HSPB1POLBALDH1A1ACHEHSD17B10
Ethane SCHEMBL28251595 0.95 HSPB1 (0.69) HSPB1POLBALDH1A1ACHEHSD17B10
Methyl Alcohol SCHEMBL28785209 0.93 HSPB1 (0.67) HSPB1POLBALDH1A1ACHEHSD17B10
SCHEMBL2961612 0.93 HSPB1 (0.67) HSPB1POLBALDH1A1ACHEHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13038 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118305-A Preparation method of bio-based isosorbide-based semi-aromatic polyamide 江苏泰阿生物技术有限公司 2025-06-10 CN claimed
CN-116478047-B Method for synthesizing p-fluoroaniline by catalytic hydrogenation of p-fluoronitrobenzene 安庆时联新材料有限责任公司 2025-06-03 CN claimed
CN-120037950-A Hydrogenation catalyst, preparation method and application thereof, and aromatic nitro compound hydrogenation method 中国石油化工股份有限公司 2025-05-27 CN claimed
CN-120044666-A Temperature-resistant and high-pressure-resistant distributed optical cable for well logging and processing method thereof 东莞市光佳光电科技有限公司 2025-05-27 CN claimed
CN-119972147-A Calcium carbonate/carbon composite carrier supported ruthenium catalyst, preparation method and application 郑州大学 2025-05-13 CN claimed
EP-4549619-A1 PREPARATION OF AMINES BY HYDROGENATION OF NITRO COMPOUNDS USING HYDROGEN WITH LOW DEUTERIUM CONTENT BASF SE (DE) 2025-05-07 EP claimed
CN-119912346-A Ultra-large-volume low-dielectric polyimide film, preparation method and application 安徽国风新材料技术有限公司 2025-05-02 CN claimed
CN-119081175-B Preparation process of light and soft label film 江苏金大包装材料科技有限公司 2025-04-25 CN claimed
CN-119819295-A Preparation method and application method of silver catalyst 宁夏银飞医药科技有限公司 2025-04-15 CN claimed
CN-115894251-B Diamine monomer containing pyrene and triphenylamine structures, preparation method of diamine monomer, polyimide, preparation method of polyimide and application of polyimide 中山大学 2025-04-11 CN claimed
EP-0081790-A1 p-Phenylene diamines, their preparation and use Henkel Kommanditgesellschaft auf Aktien (DE) 1983-06-22 EP claimed
EP-0078709-A2 Preparation of nitroaralkyl cyanides and derivatives thereof ETHYL CORPORATION (US) 1983-05-11 EP claimed
EP-0023706-B1 4-PHENOXY PIPERIDINES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1983-03-02 EP claimed
US-4375550-A Hydrogenation of halogen-substituted aromatic nitro compounds JOHNSON, MATTHEY & CO., LIMITED (GB) 1983-03-01 US claimed
US-4370278-A Nucleophilic substitution process ETHYL CORPORATION (US) 1983-01-25 US claimed
EP-0055386-A2 Hair-dyeing preparations Henkel Kommanditgesellschaft auf Aktien (DE) 1982-07-07 EP claimed
US-4287374-A Process for the production of fluoronitrobenzenes THE BOOTS COMPANY (GB) 1981-09-01 US claimed
EP-0023706-A1 4-Phenoxy piperidines, process for their preparation, their use and medicaments containing them Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1981-02-11 EP claimed
US-4164517-A REACTING A CHLORONITROBENZENE WITH POTASSIUM FLUORIDE IN SULFOLANE I.S.C. CHEMICALS LIMITED (GB) 1979-08-14 US claimed
US-3982958-A HERMETICALLY SEALED UNION CARBIDE CORPORATION (US) 1976-09-28 US claimed