Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 11/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960237 | 1.00 | TBXAS1 (0.36) | TBXAS1NOS1HRH1HRH3HRH2 | |
| SCHEMBL6958742 | 1.00 | TBXAS1 (0.36) | TBXAS1NOS1HRH1HRH3HRH2 | |
| SCHEMBL6956227 | 1.00 | TBXAS1 (0.36) | TBXAS1NOS1HRH1HRH3HRH2 | |
| SCHEMBL8176755 | 1.00 | TBXAS1 (0.36) | TBXAS1NOS1HRH1HRH3HRH2 | |
| SCHEMBL6956307 | 0.99 | TBXAS1 (0.34) | TBXAS1NOS1HRH1HRH3HRH2 | |
| SCHEMBL7274394 | 0.80 | KDM4E (0.36) | KDM4EGAA | |
| SCHEMBL632166 | 0.71 | KDM4E (0.34) | KDM4EGAA | |
| SCHEMBL6961397 | 0.70 | — | — | |
| SCHEMBL14901212 | 0.70 | KDM4E (0.33) | KDM4EGAA | |
| SCHEMBL8172829 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882023-B1 | HISTAMINE H 3 RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2003-06-04 | — | — | EP | disclosed |