Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16125139 | 0.76 | KDM4E (0.31) | KDM4EGAAHTTTSHR | |
| SCHEMBL7274394 | 0.75 | KDM4E (0.36) | KDM4EGAAHTTTSHR | |
| SCHEMBL20309525 | 0.75 | KDM4E (0.33) | KDM4EGAA | |
| Hydrochloric Acid SCHEMBL7277644 | 0.74 | KDM4E (0.36) | KDM4EGAAHTTTSHR | |
| SCHEMBL632166 | 0.72 | KDM4E (0.34) | KDM4EGAAHTTTSHR | |
| SCHEMBL6956307 | 0.71 | TBXAS1 (0.34) | KDM4EGAAHTTTSHR | |
| SCHEMBL6958742 | 0.70 | TBXAS1 (0.36) | KDM4EGAA | |
| SCHEMBL6964096 | 0.70 | TBXAS1 (0.36) | KDM4EGAA | |
| SCHEMBL6429138 | 0.67 | ALDH1A1 (0.39) | KDM4EGAAHTTTSHR | |
| SCHEMBL9217956 | 0.65 | ALDH1A1 (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013061080-A1 | ANTICANCER PYRIDOPYRAZINES VIA THE INHIBITION OF FGFR KINASES | ASTEX THERAPEUTICS LIMITED (GB) | 2013-05-02 | — | — | WO | disclosed |