Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965520 | 0.86 | CA12 (0.45) | SMN1; SMN2HSD17B10MEN1KMT2APKM | |
| SCHEMBL6966156 | 0.84 | MEN1 (0.51) | SMN1; SMN2MEN1KMT2APOLBATM | |
| SCHEMBL6964461 | 0.79 | FFAR4 (0.47) | MEN1KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL9432132 | 0.77 | CA9 (0.50) | SMN1; SMN2KMT2ALMNAATMALDH1A1 | |
| SCHEMBL11709342 | 0.77 | KMT2A (0.44) | SMN1; SMN2HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL2337256 | 0.75 | REN (0.44) | SMN1; SMN2HSD17B10IDO1MEN1KMT2A | |
| SCHEMBL6959194 | 0.75 | CA2 (0.59) | MEN1KMT2ALMNAALDH1A1CA12 | |
| SCHEMBL2207149 | 0.75 | IDO1 (0.56) | SMN1; SMN2IDO1KMT2APOLBLMNA | |
| SCHEMBL14593746 | 0.75 | VDR (0.45) | SMN1; SMN2HSD17B10MEN1KMT2APKM | |
| SCHEMBL9316876 | 0.74 | CA12 (0.47) | SMN1; SMN2HSD17B10MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729465-B1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & CO (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6005103-A | TREATMENT OF BACTERIAL AND VIRAL INFECTIONS AND DISEASES, INCLUDING AIDS | WARNER-LAMBERT COMPANY (US) | 1999-12-21 | — | — | US | disclosed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |