Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | RBP4 | P02753 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 10/20 | 0.52 |
| ▸ | HTR1D | P28221 | 10/20 | 0.52 |
| ▸ | HTR1B | P28222 | 10/20 | 0.52 |
| ▸ | HTR2C | P28335 | 4/20 | 0.51 |
| ▸ | HTR6 | P50406 | 4/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954910 | 0.91 | MAPT (0.53) | MAPTRAB9ARBP4HTR1AHTR1D | |
| SCHEMBL6963523 | 0.91 | MAPT (0.60) | MAPTRAB9ARBP4HTR1AHTR1D | |
| SCHEMBL6962010 | 0.82 | RBP4 (0.57) | RAB9ARBP4HTR1AHTR1DHTR1B | |
| SCHEMBL6956583 | 0.82 | KMT2A (0.53) | MAPTRBP4FAAHKDM4EMAPK1 | |
| SCHEMBL6966945 | 0.81 | MAPT (0.57) | MAPTRAB9ARBP4HTR1AHTR1D | |
| SCHEMBL6961396 | 0.81 | PANK3 (0.63) | MAPTHTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL6960999 | 0.81 | KDM4E (0.52) | PANK3KDM4E | |
| SCHEMBL6961546 | 0.80 | KDM4E (0.48) | MAPTRBP4HTR1AFAAHPANK3 | |
| SCHEMBL6961576 | 0.80 | HTR1A (0.55) | MAPTRAB9ARBP4HTR1AHTR1D | |
| SCHEMBL6952726 | 0.80 | MAPT (0.55) | MAPTRAB9AFAAHPANK3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |