Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033909 | 0.83 | ALDH1A1 (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2089515 | 0.82 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4256324 | 0.80 | ALDH1A1 (0.40) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL20560687 | 0.80 | ALDH1A1 (0.40) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29838495 | 0.80 | L3MBTL1 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5464387 | 0.80 | L3MBTL1 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2089517 | 0.78 | KMT2A (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28822520 | 0.77 | ALDH1A1 (0.49) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6185781 | 0.76 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9837431 | 0.76 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |