Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955335 | 0.86 | CYP2D6 (0.47) | KMT2ASMN1; SMN2MEN1CYP2D6CYP2C9 | |
| SCHEMBL6955537 | 0.82 | CYP2D6 (0.47) | L3MBTL1KMT2ASMN1; SMN2MEN1CYP2D6 | |
| SCHEMBL6955643 | 0.82 | L3MBTL1 (0.46) | L3MBTL1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL6969126 | 0.80 | L3MBTL1 (0.45) | L3MBTL1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL6969761 | 0.79 | L3MBTL1 (0.43) | L3MBTL1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL6957385 | 0.76 | AVPR1A (0.52) | — | |
| SCHEMBL7140109 | 0.75 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL6971802 | 0.74 | SMN1; SMN2 (0.44) | L3MBTL1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL6955542 | 0.73 | ALDH1A1 (0.43) | L3MBTL1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL6965409 | 0.73 | SMN1; SMN2 (0.47) | L3MBTL1KMT2ASMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |