Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970670 | 0.85 | CYP2D6 (0.51) | CYP2D6CYP2C9HPGDALDH1A1P2RX4 | |
| SCHEMBL6960057 | 0.83 | PDE4A (0.43) | CYP2D6CYP2C9ALDH1A1MAPTKMT2A | |
| SCHEMBL6964440 | 0.82 | L3MBTL1 (0.46) | CYP2D6CYP2C9HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL6955542 | 0.78 | ALDH1A1 (0.43) | HPGDL3MBTL1ALDH1A1MAPTBCHE | |
| SCHEMBL6958687 | 0.77 | DRD3 (0.46) | CYP2D6HPGDL3MBTL1ALDH1A1MAPT | |
| SCHEMBL7352575 | 0.76 | ALDH1A1 (0.56) | HPGDL3MBTL1ALDH1A1MAPTBCHE | |
| SCHEMBL6968459 | 0.75 | BCHE (0.56) | HPGDL3MBTL1ALDH1A1MAPTBCHE | |
| SCHEMBL7330871 | 0.74 | ALDH1A1 (0.46) | HPGDL3MBTL1ALDH1A1MAPTBCHE | |
| SCHEMBL7140109 | 0.74 | L3MBTL1 (0.45) | HPGDL3MBTL1ALDH1A1MAPTBCHE | |
| SCHEMBL7330866 | 0.74 | ALDH1A1 (0.46) | HPGDL3MBTL1ALDH1A1MAPTBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |