Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678848 | 0.74 | MTOR (0.34) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7673189 | 0.74 | MTOR (0.34) | ADRA1DADRA1AADRA1B | |
| SCHEMBL5663717 | 0.74 | MTOR (0.34) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7678845 | 0.74 | MTOR (0.34) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL6958159 | 0.73 | ADRA1D (0.62) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7678945 | 0.72 | MTOR (0.34) | ADRA1A | |
| SCHEMBL7678949 | 0.72 | MTOR (0.34) | ADRA1A | |
| SCHEMBL5660734 | 0.70 | HCAR3 (0.39) | TNKSADRA1DADRA1AADRA1BHCAR3 | |
| SCHEMBL14587408 | 0.70 | HCAR3 (0.36) | TNKSADRA1DADRA1AADRA1BHCAR3 | |
| SCHEMBL14619731 | 0.64 | TNKS (0.37) | TNKSHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988295-A4 | HETEROCYCLIC SUBSTITUTED PIPERIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 2003-08-13 | — | — | EP | disclosed |
| EP-0988295-A1 | HETEROCYCLIC SUBSTITUTED PIPERIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998057940-A1 | HETEROCYCLIC SUBSTITUTED PIPERIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-12-23 | — | — | WO | disclosed |